The association between COVID-19 and autoimmune diseases is an important area of research, as the virus may trigger autoimmune responses or worsen pre-existing autoimmune conditions. COVID-19 can potentially overstimulate the immune system, leading to flares in conditions like lupus, rheumatoid arthritis, or multiple sclerosis. Conversely, those with autoimmune diseases may be at higher risk of severe COVID-19 complications. Managing both the disease and immune response is crucial, with special considerations for treatments and vaccinations. Always consult a healthcare provider for personalized advice.